Developments On 1,2,4-Triazine Scaffold Substitutions For Possible Anticancer Agents

Recent literature studies reveal that heterocyclic scaffolds containing a 1,2,4-triazine ring have gained due significance owing to their pharmacological relevance. This article gives an insight on the different methods used for synthesis of 1,2,4-triazine, its derivatives such as N-oxides, N,N’-dioxides, benzo and hetero-fused systems. The main focus will be on the anti-cancer activities of the 1,2,4-triazine moiety.