Open AccessTakotsubo syndrome early after treatment due to non cardiotoxic chemotherapy agents
Author(s) -
Benay Özbay,
Ecem Gürses,
Hatice Kemal,
Evrim Şimşek,
Hakan Kültürsay
Publication year - 2020
Publication title -
türk kardiyoloji derneği arşivi
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.2
H-Index - 24
ISSN - 1016-5169
DOI - 10.5543/tkda.2020.25590
Subject(s) - vinorelbine , gemcitabine , medicine , cardiotoxicity , chemotherapy , cardiomyopathy , myocardial infarction , heart failure , chemotherapeutic drugs , cancer , cardiology , oncology , intensive care medicine , cisplatin
Takotsubo syndrome (TTS), acute stress-induced cardiomyopathy, is known to have a dramatic clinical presentation mimicking acute myocardial infarction. Recently developed chemotherapeutic drugs have resulted in improvements in morbidity and mortality in many forms of cancer. However, some chemotherapeutic drugs are cardiotoxic and may cause heart failure. Gemcitabine and vinorelbine are commonly used drugs for various solid organ neoplasms. While neither of these chemotherapeutic drugs has been directly associated with cardiotoxicity, there are a few case reports in the literature related to gemcitabine treatment- induced cardiomyopathy. This case report describes a case of TTS developing within hours of gemcitabine and vinorelbine chemotherapy.