Open AccessA multivariate analysis approach on identifying of influencing factors and the chance of development of diabetic eye disease among diabetes in a diabetic Centre of Southwestern Malabar region of India
Author(s) -
Amitha Prasad,
AUTHOR_ID,
Senthilvel Vasudevan,
AUTHOR_ID
Publication year - 2021
Publication title -
international journal of medical sciences and nursing research
Language(s) - English
Resource type - Journals
ISSN - 2583-0996
DOI - 10.55349/ijmsnr.20211259
Subject(s) - medicine , diabetes mellitus , confounding , logistic regression , diabetic retinopathy , disease , observational study , blood sugar , multivariate analysis , type 2 diabetes mellitus , non communicable disease , cross sectional study , endocrinology , pathology
Background: Diabetic Retinopathy is a non-communicable disease and metabolic disorder. It is a public health problem in Worldwide. In this paper, finding influencing factors and how much probability to development of DR among known T2DM patients. Materials and Methods: This was a hospital-based cross-sectional and observational study among T2DM patients, with and without DR in the diabetes clinic with sample of 150 patients. Statistical analysis used chi-square and binary logistic regression analysis was used to identify correlates of DR after controlling of confounders. Results: In this present study, among 150 patients, 39 (26%) patients had DR. Smoking habit was strongly associated with development of DR (AOR=15.39, p=0.002), patients had history of hypertension was associated with DR (AOR=1.10, p=0.016), medication, in that insulin users were strongly associated with DR (AOR=5.72, p=0.002), duration of diabetes mellitus with >10 years was associated with DR (AOR=1.18, p=0.001), total cholesterol with abnormal was 5-fold more increase in risk with the development of DR (AOR=5.86, p=0.065) but not significant, high hba1c with >6.5% was associated with the progression of DR (AOR=1.34, p=0.035), and fasting blood sugar with abnormal was associated with the progression of DR (AOR=1.01, p=0.027) except age but, showed positive association with DR. Probability of developing DR in a T2DM patient was 98%. Conclusion: From this study, we revealed that influencing variables were hba1c, smoking habit, intake of tablet/insulin, duration of DM, history of hypertension and fasting blood sugar. The chance/probability of developing retinopathy was very high among known diabetes patients those who had longer duration of DM. Hence, we have recommended a periodic eye screening is mandatory in T2DM patients. Keywords: diabetes mellitus, diabetic retinopathy, influencing factors, probability, multivariate analysis