Open AccessPure mucinous (colloid) adenocarcinoma of the gallbladder – a rare phenotype
Author(s) -
Gupte Prajakta,
Chaturvedi Rachana,
Patil Lalita,
Joshi Amita
Publication year - 2013
Publication title -
oncology, gastroenterology and hepatology reports
Language(s) - English
Resource type - Journals
eISSN - 2348-3113
pISSN - 2278-8921
DOI - 10.5530/ogh.2013.1.8
Subject(s) - gallbladder , adenocarcinoma , phenotype , medicine , colloid , pathology , gastroenterology , oncology , cancer , biology , chemistry , genetics , gene
Mucinous carcinomas are very rare in the biliary tract. Only twenty cases of mucinous carcinomas of the
gallbladder have been reported so far of which the pure mucinous (colloid) phenotype is exceedingly rare.
We report one such rare case of a 55 year old lady with history of exposure to barium fumes in the past, who
presented to our hospital with features of biliary obstruction. Radiological examination revealed neoplastic
thickening of the gallbladder along with cholelithiasis and choledocholithiasis. Cholecystectomy was performed
and the specimen showed thickened gallbladder wall with a glistening grey white infiltrative growth. Microscopy
showed pure mucinous (colloid) adenocarcinoma, the entire tumor being composed of pools of extracellular
mucin with clusters of tumor cells floating in them with no other component