Open AccessHepatorenal syndrome: Update on diagnosis and treatment
Author(s) -
Olga Baraldi,
Chiara Valentini,
Gabriele Donati,
Giorgia Comai,
Vania Cuna,
Irene Capelli,
Maria Laura Angelini,
Maria Ilaria Moretti,
Andrea Angeletti,
Fabio Piscaglia,
Gaetano La Manna
Publication year - 2015
Publication title -
world journal of nephrology
Language(s) - English
Resource type - Journals
ISSN - 2220-6124
DOI - 10.5527/wjn.v4.i5.511
Subject(s) - hepatorenal syndrome , medicine , acute kidney injury , intensive care medicine , cirrhosis , kidney disease , clinical practice , disease , complication , liver failure , renal replacement therapy , therapeutic approach , physical therapy
Acute kidney injury (AKI) is a common complication in patients with end-stage liver disease and advanced cirrhosis regardless of the underlying cause. Hepatorenal syndrome (HRS), a functional form of kidney failure, is one of the many possible causes of AKI. HRS is potentially reversible but involves highly complex pathogenetic mechanisms and equally complex clinical and therapeutic management. Once HRS has developed, it has a very poor prognosis. This review focuses on the diagnostic approach to HRS and discusses the therapeutic protocols currently adopted in clinical practice.