Open AccessHEMATOLOGICAL AND SEROLOGICAL PARAMETERS FOR DETECTION OF COVID-19
Author(s) -
Abduladheem Turki Jalil,
Mustafa Tareq Shanshool,
Saja Hussain Dilfy,
Marwan Mahmood Saleh,
Ahmed AbdulJabbar Suleiman
Publication year - 2022
Publication title -
journal of microbiology, biotechnology and food sciences
Language(s) - English
Resource type - Journals
ISSN - 1338-5178
DOI - 10.55251/jmbfs.4229
Subject(s) - mean corpuscular volume , medicine , mean platelet volume , white blood cell , hematocrit , gastroenterology , serology , immunology , c reactive protein , hemoglobin , covid-19 , mean corpuscular hemoglobin concentration , outbreak , platelet , antibody , disease , pathology , infectious disease (medical specialty) , inflammation
Coronavirus disease (COVID-19) appeared as outbreak in 2019 in Wuhan, China. It has been classified as pandemic disease and more severe than predicted; with infections already recorded in a variety of countries. This study aims to confirm the COVID-19 infection through the following tests: hematological, C-reactive protein (CRP). Samples were collected from the infected patients and sent to the National Flu Center (Central Public Health Laboratory) for COVID-19 (positive or negative) diagnosis by the RT-PCR technique. In this study, sixty five of COVID-19 patients and twenty five of healthy control samples male and female were collected in Iraq. There are significant differences in the parameters of the hematological markers for patients in comparing with the control group and no significant differences were observed in Hb when RBC and GRAN percent rise in patients relative to the control group with P=0.0395 and P=0.0354 respectively comparing with the control group. White blood cells (WBC), Lymphocyte (LYM%), Platelets (PIT), monocyte (Mid%), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean platelet volume (MPV), plateletcrit (PCT) was drop dramatically in patients compared to control group. Fifty-one of patients for whom the test was given exhibited a positive (CRP) result. Likewise, the results showed that few patients were negative to CRP test. The Hematological parameters levels (HCT, MCV, MCH, Pelt, WBC, LYM, Mid, MPV, PCT) decreased, but Hb, RBC, GRAN% increased. C-reactive protein test showed a positive result in 85% of patients which can be considered an indicator for predicting severity infection with COVID-19.