Open Access[NMP][HSO4 ]-MEDIATED ENVIRONMENTALLY BENIGN SYNTHESIS OF 4-THIAZOLIDINONE DERIVATIVES
Author(s) -
Vishal U Mane,
Satish M. Chavan,
Waseem A Beg,
Dhananjay V. Mane
Publication year - 2022
Publication title -
journal of advanced scientific research
Language(s) - English
Resource type - Journals
ISSN - 0976-9595
DOI - 10.55218/jasr.202213202
Subject(s) - ionic liquid , chemistry , microwave irradiation , brønsted–lowry acid–base theory , solvent , environmentally friendly , combinatorial chemistry , reaction conditions , organic chemistry , catalysis , ecology , biology
A N-methyl-2-pyrrolidonium hydrogensulfate [NMP][HSO4] bronsted acidic ionic liquid-promoted cyclocondensation-cyclization pathway has been established using one pot reaction of anilines, aldehydes and mercaptoacetic acid to give 4-thiazolidinone derivatives in good to promising yields using microwave irradiation. Applications for this protocol are easy workup, high yields, short reaction times, variability of functional groups, recyclability and solvent-free conditions.