Open AccessDoes vitamin D affects components of the metabolic syndrome?
Author(s) -
S Karahan-Yilmaz,
Ahmed Ayaz
Publication year - 2015
Publication title -
türk hijyen ve deneysel biyoloji dergisi/türk hijiyen ve deneysel biyoloji dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.171
H-Index - 5
eISSN - 1308-2523
pISSN - 0377-9777
DOI - 10.5505/turkhijyen.2015.46693
Subject(s) - metabolic syndrome , vitamin d and neurology , medicine , endocrinology , diabetes mellitus
Metabolic syndrome is a major public healthproblem which has become increasingly commonworlwide with cardiometabolic complications andhave high morbidity and mortality. In addition tosome genetical features, environmental factorssuch sedentary lifestyle, improper eating habitsconstitutes a risk factor for metabolic syndrome.Important components of the metabolic syndromeare dyslipidemia (low HDL levels, high triglycerideslevel), hyperglycemia, elevated blood pressure andabdominal obesity. Forming metabolic syndromeof other than the five main components, insulinresistance on the basis thought to play a role inseveral clinical implications of this syndrome isconsidered. Clinical implications of the metabolicsyndrome are; diabetes, essential hypertension,visceral obesity, cardiovascular disorders, insulinresistance, osteoporosis, polycystic ovary syndrome,dyslipidemia, hypercoagulability, hyperuricemia,bone mineral density, fatty liver disease and sleepapnea. In recent years, it is suggested that vitaminD prevents the occurrence of diseases caused byobesity and insulin resistance and the lack of itfacilitates occurence of these diseases. VitaminD deficiency is a public health problem with agrowing prevalence in developed and developingcountries. Vitamin D is a fat-soluble vitamin, butit is synthesized in the body and affect also otherregions it is expressed in the body. Because of thisit is described as a hormone in the present day.As well as its known positive effects on calciumbalance, it has also physiological functions relatedthe endocrine system. The best indicator showing the level of vitamin D is serum 25 (OH) D level. VitaminD intake and 25 (OH) D levels are reported to beassociated with obesity, metabolic syndrome anddiabetes. Diseases which are mostly researchedabout relation between Vitamin D are cardiovasculardisease, kidney disease, diabetes, obesity, metabolicsyndrome. In this review, evaluation of the effectsof Vitamin D on the metabolic syndrome componentsof insulin resistance, diabetes, obesity, hypertension,dyslipidemia, cardiovascular disease, fatty liverdisease, polycystic ovary syndrome and bone mineraldensity, was aimed