Open AccessUnilateral exudative retinal detachment as the sole presentation of relapsing acute lymphoblastic leukemia
Author(s) -
Fatih Mehmet Azık,
Arsen Akıncı,
Tülin Revide Şaylı,
Vildan Çulha,
Kuddusi Teberik,
Mehmet Yasin Teke,
Fatih Gürbüz
Publication year - 2012
Publication title -
turkish journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.351
H-Index - 16
ISSN - 1300-7777
DOI - 10.5505/tjh.2012.72623
Subject(s) - medicine , fundus (uterus) , retinal detachment , leukemia , enucleation , acute leukemia , retina , ophthalmology , retinal , surgery , physics , optics
Ocular findings are rarely the initial symptom of leukemia, although up to 90% of all leukemia patients have fundus changes during the course of the disease. Herein we report a relapsing acute lymphoblastic leukemia patient with thesole presentation of sudden visual loss and exudative retinal detachment. An 8-year-old boy with acute lymphoblasticleukemia developed sudden visual loss during his first remission period. Bullous retinal detachment with total afferentpupillary defect was observed. Orbital magnetic resonance imaging revealed an intraocular mass lesion; simultaneouslyobtained bone marrow and cerebrospinal fluid samples showed no evidence of leukemic cells. Following local irradiation,and systemic and intrathecal chemotherapy the mass disappeared. Local irradiation, and systemic and intrathecalchemotherapy effectively controlled the isolated ocular relapse of acute lymphoblastic leukemia and eliminated the needfor enucleation.