Open AccessUtility of functional magnetic resonance imaging techniques in the diagnosis of chronic consciousness disorders
Author(s) -
Halil Önder,
Ethem Murat Arsava,
Demet Funda Baş,
Kader Karlı Oğuz,
Mehmet Akif Topçuoğlu
Publication year - 2016
Publication title -
türk beyin damar hastalıkları dergisi/türk beyin damar hastalıkları dergisi
Language(s) - English
Resource type - Journals
eISSN - 2146-9113
pISSN - 1301-1375
DOI - 10.5505/tbdhd.2016.96168
Subject(s) - functional magnetic resonance imaging , magnetic resonance imaging , persistent vegetative state , consciousness , nuclear magnetic resonance , medicine , psychology , neuroscience , radiology , physics , minimally conscious state
Diagnosis of (persistent) vegetative state (PVS), minimally consciousness state (MCS) or mesencephalic "locked-in" syndrome (LIS) is challenging resting only on clinical grounds in cases awakening from acute comatose states with eye opening but no consistent cooperativeness. These descriptions are of uttermost critical importance in terms of prognosis declaration and treatment level selection. Stimulus-evoked and task-evoked functional magnetic resonance imaging (fMRI) or resting state fMRI can be used for this purpose. Three cases, in whom convincing discrimination of PVS, LIS and MCS was impossible to be clinically attained are herein presented and discussed. For the sake of fMRI technology, diagnoses of LIS connected to pontomesencephalic infarction, PVD due to pontine hemorrhage and MBD from global cerebral ischemia could be insured. Utility of fMRI in the neurocritical care and neurovascular disease practices is briefly presented