Open AccessA case of palmoplantar dysesthesia syndrome caused by capecitabine
Author(s) -
Ömer Faruk Elmas,
Mahmut Sami Metin,
Okan Kızılyel,
Akın Aktaş,
Canan Birdal
Publication year - 2015
Publication title -
ağrı
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.255
H-Index - 19
eISSN - 2458-9446
pISSN - 1300-0012
DOI - 10.5505/agri.2014.32559
Subject(s) - capecitabine , dysesthesia , medicine , epirubicin , docetaxel , dermatology , erythema , oncology , chemotherapy , surgery , cancer , cyclophosphamide , colorectal cancer
Palmoplantar dysesthesia is a dermatologic toxic reaction caused by chemotherapeutics. Also known as hand-foot syndrome, it is not life-threatening, but does decrease quality of life. Dysesthesia, erythema, edema, and desquamation on palmoplantar region are observed clinically. Palmoplantar dysesthesia syndrome may be caused by chemotherapeutics including cytarabine, doxorubicin, capecitabine, epirubicin, docetaxel, vinorelbine, and 5-fluorouracil. The case of a 62-year-old woman who presented with diffuse erythema on palmoplantar area after use of capecitabine for metastatic breast carcinoma is described in the present report. Palmoplantar dysesthesia syndrome caused by capecitabine may affect patient compliance.