Determination of 50% endpoint titer using a simple formula | Zendy

Muthannan Andavar Ramakrishnan | Zendy

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Determination of 50% endpoint titer using a simple formula

Author(s) -

Muthannan Andavar Ramakrishnan

Publication year - 2016

Publication title -

world journal of virology

Language(s) - English

Resource type - Journals

ISSN - 2220-3249

DOI - 10.5501/wjv.v5.i2.85

Subject(s) - simple (philosophy) , serial dilution , titer , mathematics , medicine , statistics , calculus (dental) , immunology , pathology , philosophy , alternative medicine , dentistry , epistemology , antibody

Two commonly used methods for calculating 50% endpoint using serial dilutions are Spearman-Karber method and Reed and Muench method. To understand/apply the above formulas, moderate statistical/mathematical skills are necessary. In this paper, a simple formula/method for calculating 50% endpoints has been proposed. The formula yields essentially similar results as those of the Spearman-Karber method. The formula has been rigorously evaluated with several samples.

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