Open AccessSARS-CoV-2 Omicron variant (B.1.1.529): A concern with immune escape
Author(s) -
Adekunle Sanyaolu,
Aleksandra Marinkovic,
Stephanie Prakash,
Nafees Haider,
Martina Williams,
Chuku Okorie,
Olanrewaju Badaru,
Stella Ifeanyi Smith
Publication year - 2022
Publication title -
world journal of virology
Language(s) - English
Resource type - Journals
ISSN - 2220-3249
DOI - 10.5501/wjv.v11.i3.137
Subject(s) - transmissibility (structural dynamics) , covid-19 , immune escape , immune system , immunity , medicine , virology , immunology , biology , disease , pathology , outbreak , physics , vibration isolation , quantum mechanics , infectious disease (medical specialty) , vibration
Omicron, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant that is now spreading across the world, is the most altered version to emerge so far, with mutations comparable to changes reported in earlier variants of concern linked with increased transmissibility and partial resistance to vaccine-induced immunity. This article provides an overview of the SARS-CoV-2 variant Omicron (B.1.1.529) by reviewing the literature from major scientific databases. Although clear immunological and clinical data are not yet available, we extrapolated from what is known about mutations present in the Omicron variant of SARS-CoV-2 and offer preliminary indications on transmissibility, severity, and immune escape through existing research and databases.