Open AccessPerioperative effects of high doses of intraoperative thymoglobulin induction in liver transplantation
Author(s) -
Lesley De Pietri,
Valentina Serra,
Giuseppe Preziosi,
Gianluca Rompianesi,
B. Begliomini
Publication year - 2015
Publication title -
world journal of transplantation
Language(s) - English
Resource type - Journals
ISSN - 2220-3230
DOI - 10.5500/wjt.v5.i4.320
Subject(s) - thymoglobulin , medicine , perioperative , transplantation , anesthesia , chills , surgery , liver transplantation , leukopenia , gastroenterology , kidney transplantation , chemotherapy
To describe our single-centre experience in liver transplantation (LT) with the infusion of high perioperative thymoglobulin doses. The optimal dosage and timing of thymoglobulin(®) [antithymocyte globulin (ATG)] administration during LT remains controversial. Cytokine release syndrome, haemolytic anaemia, thrombocytopenia, neutropenia, fever and serum sickness are potential adverse effects associated with ATG infusion.