Role of IL-10 in the progression of kidney disease | Zendy

Inna Sinuani | Zendy; Ilia Beberashvili | Zendy; Zhan Averbukh | Zendy; Judith Sandbank | Zendy

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Role of IL-10 in the progression of kidney disease

Author(s) -

Inna Sinuani,

Ilia Beberashvili,

Zhan Averbukh,

Judith Sandbank

Publication year - 2013

Publication title -

world journal of transplantation

Language(s) - English

Resource type - Journals

ISSN - 2220-3230

DOI - 10.5500/wjt.v3.i4.91

Subject(s) - kidney disease , kidney , cytokine , medicine , disease , acute kidney injury , inflammation , renal stem cell , interleukin , immunology , bioinformatics , biology , microbiology and biotechnology , stem cell , progenitor cell

Interleukin-10 (IL-10), a cytokine with anti-inflammatory and immunomodulatory functions, regulates the biology of B and T cells. The present review describes the role of IL-10 in normal renal physiology, during acute kidney injury and in the development of chronic renal failure. We further discuss IL-10-induced cellular and molecular pathways and their link to the progression of kidney injury.

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