Open AccessmTOR signaling in liver regeneration: Rapamycin combined with growth factor treatment
Author(s) -
Suomi M. G. Fouraschen,
Petra E. de Ruiter,
Jaap Kwekkeboom,
Ron Wf de Bruin,
Geert Kazemier,
Herold J. Metselaar,
Hugo W. Tilanus,
L.J. van der Laan,
Jeroen de Jonge
Publication year - 2013
Publication title -
world journal of transplantation
Language(s) - English
Resource type - Journals
ISSN - 2220-3230
DOI - 10.5500/wjt.v3.i3.36
Subject(s) - hepatocyte growth factor , pi3k/akt/mtor pathway , liver regeneration , hepatocyte , alanine transaminase , medicine , biology , angiogenesis , autophagy , endocrinology , andrology , regeneration (biology) , signal transduction , receptor , biochemistry , apoptosis , in vitro , microbiology and biotechnology
To investigate the effects of mammalian target of rapamycin (mTOR) inhibition on liver regeneration and autophagy in a surgical resection model.