Open AccessExploring the safety and efficacy of adding ketoconazole to tacrolimus in pediatric renal transplant immunosuppression
Author(s) -
Sindy Méndez,
Brooke M Ramay,
Angie Aguilar-González,
Randall LouMeda
Publication year - 2020
Publication title -
world journal of transplantation
Language(s) - English
Resource type - Journals
ISSN - 2220-3230
DOI - 10.5500/wjt.v10.i11.356
Subject(s) - tacrolimus , immunosuppression , ketoconazole , medicine , renal transplant , transplantation , dermatology , antifungal
Guatemala is a developing country in Central America with limited health resources. In order to expand successful renal transplant care to children and adolescents at the lowest possible cost, our pediatric renal transplant clinic uses a post-transplant tacrolimus-sparing strategy via inhibition of CYP3A4.