Open AccessDeep brain stimulation for obsessive-compulsive disorder: A systematic review of worldwide experience after 20 years
Author(s) -
Lorea Mar-Barrutia,
Eva Real,
Cinto Segalàs,
Sara Bertolín,
José M. Menchón,
Pino Alonso
Publication year - 2021
Publication title -
world journal of psychiatry
Language(s) - English
Resource type - Journals
ISSN - 2220-3206
DOI - 10.5498/wjp.v11.i9.659
Subject(s) - deep brain stimulation , medicine , obsessive compulsive , brain stimulation , psychiatry , stimulation , clinical psychology , neuroscience , psychology , disease , parkinson's disease
Twenty years after its first use in a patient with obsessive-compulsive disorder (OCD), the results confirm that deep brain stimulation (DBS) is a promising therapy for patients with severe and resistant forms of the disorder. Nevertheless, many unknowns remain, including the optimal anatomical targets, the best stimulation parameters, the long-term (LT) effects of the therapy, and the clinical or biological factors associated with response. This systematic review of the articles published to date on DBS for OCD assesses the short and LT efficacy of the therapy and seeks to identify predictors of response.