Open AccessImpact and risk factors of post-stroke bone fracture
Author(s) -
Kang Huo,
Syed I Hashim,
Kimberley L Y Yong,
Hua Su,
Qing Qu
Publication year - 2016
Publication title -
world journal of experimental medicine
Language(s) - English
Resource type - Journals
ISSN - 2220-315X
DOI - 10.5493/wjem.v6.i1.1
Subject(s) - medicine , osteoporosis , stroke (engine) , teriparatide , bone mineral , risk factor , bone fracture , bone density conservation agents , bone resorption , physical therapy , radiology , mechanical engineering , engineering
Bone fracture occurs in stroke patients at different times during the recovery phase, prolonging recovery time and increasing medical costs. In this review, we discuss the potential risk factors for post-stroke bone fracture and preventive methods. Most post-stroke bone fractures occur in the lower extremities, indicating fragile bones are a risk factor. Motor changes, including posture, mobility, and balance post-stroke contribute to bone loss and thus increase risk of bone fracture. Bone mineral density is a useful indicator for bone resorption, useful to identify patients at risk of post-stroke bone fracture. Calcium supplementation was previously regarded as a useful treatment during physical rehabilitation. However, recent data suggests calcium supplementation has a negative impact on atherosclerotic conditions. Vitamin D intake may prevent osteoporosis and fractures in patients with stroke. Although drugs such as teriparatide show some benefits in preventing osteoporosis, additional clinical trials are needed to determine the most effective conditions for post-stroke applications.