Open AccessNeutrophil-lymphocyte ratio: A prognostic tool in patients with in-hospital cardiac arrest
Author(s) -
Vishal Patel,
Philip Vendittelli,
Rajat Garg,
Susan Szpunar,
Thomas LaLonde,
John Lee,
Howard Rosman,
Rajendra H. Mehta,
Hussein Othman
Publication year - 2019
Publication title -
world journal of critical care medicine
Language(s) - English
Resource type - Journals
ISSN - 2220-3141
DOI - 10.5492/wjccm.v8.i2.9
Subject(s) - medicine , sepsis , return of spontaneous circulation , retrospective cohort study , neutrophil to lymphocyte ratio , lymphocyte , adverse effect , mortality rate , area under the curve , database , intensive care medicine , emergency medicine , cardiopulmonary resuscitation , resuscitation , computer science
In-hospital cardiac arrest (IHCA) portends a poor prognosis and survival to discharge rate. Prognostic markers such as interleukin-6, S-100 protein and high sensitivity C reactive protein have been studied as predictors of adverse outcomes after return of spontaneous circulation (ROSC); however; these variables are not routine laboratory tests and incur additional cost making them difficult to incorporate and less attractive in assessing patient's prognosis. The neutrophil-lymphocyte ratio (NLR) is a marker of adverse prognosis for many cardiovascular conditions and certain types of cancers and sepsis. We hypothesize that an elevated NLR is associated with poor outcomes including mortality at discharge in patients with IHCA.