
Treatment of adult rhabdoid renal cell carcinoma with sorafenib
Author(s) -
Anil Kapoor,
Robert Tutino,
Androniki Kanaroglou,
Sébastien J. Hotte
Publication year - 2008
Publication title -
canadian urological association journal
Language(s) - English
Resource type - Journals
eISSN - 1920-1214
pISSN - 1911-6470
DOI - 10.5489/cuaj.983
Subject(s) - sorafenib , renal cell carcinoma , malignancy , tyrosine kinase inhibitor , medicine , clear cell renal cell carcinoma , oncology , tyrosine kinase , cancer research , sunitinib , pathology , hepatocellular carcinoma , cancer , receptor
Renal cell carcinoma (RCC) with rhabdoid features is an uncommon and highly aggressive malignancy. We report a case of adult clear-cell RCC with extensive rhabdoid features treated with the tyrosine kinase inhibitor sorafenib. A review of the literature summarizes important aspects of this malignancy. We discuss clinical and histological findings as well as the patient’s response to sorafenib therapy.