Open AccessThe relationship of human papillomavirus positivity with tumor characteristics in an Irish penile cancer population
Author(s) -
E Browne,
Megan Power Foley,
John O'Kelly,
Aisling Nic An Ríogh,
Nigam H. Shah,
Christine Shilling,
John P. Keane,
Pádraig Daly,
I.M. Cullen
Publication year - 2022
Publication title -
canadian urological association journal
Language(s) - English
Resource type - Journals
eISSN - 1920-1214
pISSN - 1911-6470
DOI - 10.5489/cuaj.7821
Subject(s) - penile cancer , medicine , cohort , malignancy , cancer , population , hpv infection , oncology , cervical cancer , gynecology , environmental health
Penile cancer is a rare malignancy, with a European-wide annual incidence rate of 1/100 000 males. Approximately one-third of cases are attributable to human papillomavirus (HPV) infection. p16 INK4a is a recognized surrogate marker for HPV infection in penile cancer. University Hospital Waterford (UHW) is the national referral center for penile cancer in Ireland. We report the prevalence of HPV infection and histological characteristics of an Irish penile cancer cohort using p16 INK4a as a surrogate marker.