Open AccessThe first International Penile Advanced Cancer Trial (InPACT) opens in Canada!
Author(s) -
Juanita Crook,
Peter C. Black,
Philippe E. Spiess,
Curtis A. Pettaway
Publication year - 2022
Publication title -
canadian urological association journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.477
H-Index - 38
eISSN - 1920-1214
pISSN - 1911-6470
DOI - 10.5489/cuaj.7704
Subject(s) - penile cancer , dilemma , dissection (medical) , lymph node , cancer , inguinal lymph nodes , clinical trial , medicine , surgery , philosophy , epistemology
Penile Cancer is rare in Canada and the Western world. For this reason, penile cancer lags well behind most other malignancies in the development of evidence-based guidelines for management. This dilemma was the basis for the international cooperation to develop InPACT: the International Penile Advanced Cancer Trial (NCT02305654), sponsored by both the National Cancer Institute (lead by ECOG-ACRIN Cooperative Group) and Cancer Research of the United Kingdom (CRUK). The aim of InPACT is to determine prospectively the potential benefits of chemotherapy or chemoradiation in addition to lymph node dissection in patients with clinical evidence of inguinal lymph node metastases. InPACT is now open in Canada. We will review the eligibility and randomizations.