Open AccessSynchronous metastatic seminoma and primary retroperitoneal ganglioneuroma: case report and literature review
Author(s) -
Jorg Michels,
Nicholas Van der Westhuizen,
Alison Ross
Publication year - 2013
Publication title -
canadian urological association journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.477
H-Index - 38
eISSN - 1920-1214
pISSN - 1911-6470
DOI - 10.5489/cuaj.743
Subject(s) - seminoma , ganglioneuroma , medicine , malignancy , germ cell tumors , testicular cancer , retroperitoneal space , radiology , pathology , neuroblastoma , cancer , chemotherapy , biology , genetics , cell culture
Testicular cancer is the most common malignancy in young menwith seminomas comprising almost half of all germ cell tumours.Benign ganglioneuromas are rare tumours derived from the sympatheticnervous system. They usually occur in aldolescents andyoung adults and are predominantly located in the mediastinumand retroperitoneum. We report a case of a patient with synchronousmetastatic testicular seminoma with retroperitoneal lymphnode involvement and a benign retroperitoneal ganglioneuroma(RGN) which caused diagnostic and management challenges. Thepatient had a complete response following combination chemotherapyfor his seminoma and subsequently underwent completeresection of his ganglioneuroma.