Open AccessSystematic review of therapy for men with overactive bladder
Author(s) -
Christopher Chapple
Publication year - 2013
Publication title -
canadian urological association journal
Language(s) - English
Resource type - Journals
eISSN - 1920-1214
pISSN - 1911-6470
DOI - 10.5489/cuaj.714
Subject(s) - overactive bladder , medicine , lower urinary tract symptoms , urology , urinalysis , benign prostatic hyperplasia (bph) , urinary system , gynecology , alternative medicine , pathology , prostate , cancer
Lower urinary tract symptoms (LUTS) can have multiple causes inmen. Overactive bladder (OAB) is an empirical diagnosis used asthe basis for initial management after assessing symptoms, physicalfindings, urinalysis and other indicated evaluations. In men,the diagnosis is complicated by the potential of benign prostatichyperplasia (BPH), which is a histological diagnosis. Althoughstorage symptoms (i.e., those associated with OAB) are the mostbothersome group of LUTS in men with BPH, these patients areusually treated with BPH rather than OAB drugs. The standardpharmacologic treatment of patients with bothersome voiding andstorage LUTS at low risk of progression should be an α1-AR antagonist.The combination α1-AR antagonist + antimuscarinic agentis an appropriate and valid option for male patients with voidingsymptoms and persistent storage symptoms.