Open AccessDisappearance of a major thrombus in the brachiocephalic vein without anticoagulant therapy in a patient with seminoma - a case report
Author(s) -
Hiroshi Hongo,
Hiroki Ide,
Kuniyoshi Hoshino,
Yota Yasumizu,
Yasumitsu Uchida,
Takeshi Masuda
Publication year - 2013
Publication title -
canadian urological association journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.477
H-Index - 38
eISSN - 1920-1214
pISSN - 1911-6470
DOI - 10.5489/cuaj.545
Subject(s) - medicine , brachiocephalic vein , thrombus , radiology , brachiocephalic artery , radiation therapy , thrombosis , testicular cancer , surgery , chemotherapy , aortic arch , superior vena cava , aorta
This is the first case report describing brachiocephalic vein thrombosis without compression by a metastatic tumor during chemotherapy for testicular cancer. According to previous reports of testicular cancer patients with a major thrombus, anticoagulant therapy was required to resolve all cases. However, in the present case, a major thrombus in the brachiocephalic vein disappeared without anticoagulant therapy. This 42-year-old man was diagnosed with testicular seminoma and multiple metastases to the para-aortic lymph nodes. After three cycles of cisplatin, etoposide, and bleomycin (PEB) therapy, a major thrombus in the right brachiocephalic vein was recognized on a CT scan. Although no anticoagulant therapy was undertaken, the thrombus in the right brachiocephalic vein was no longer visible on CT after the 4th cycle of PEB therapy.