Open AccessMontreal electronic artificial urinary sphincters: Our futuristic alternatives to the AMS800™
Author(s) -
Xavier Biardeau,
Sami Hached,
Oleg Loutochin,
Lysanne Campeau,
Mohamad Sawan,
Jacques Corcos
Publication year - 2017
Publication title -
canadian urological association journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.477
H-Index - 38
eISSN - 1920-1214
pISSN - 1911-6470
DOI - 10.5489/cuaj.4493
Subject(s) - cuff , ex vivo , cystometry , biomedical engineering , balloon , in vivo , catheter , artificial urinary sphincter , urethra , medicine , urinary bladder , surgery , materials science , urinary incontinence , biology , microbiology and biotechnology
We aimed to present three novel remotely controlled hydromechanical artificial urinary sphincters (AUSs) and report their in-vitro and ex-vivo results.Methods: We successively developed three distinct hydromechanical AUSs on the basis of the existing AMS800™ device by incorporating an electronic pump. No changes were made to the cuff and balloon. The AUS#1 was designed as an electromagnetically controlled device. The AUS#2 and AUS#3 were conceived as Bluetooth 2.1 remotely controlled and Bluetooth 4.0 remotelycontrolled, adaptive devices, respectively. In-vitro experiments profiled occlusive cuff pressure (OCP) during a complete device cycle, with different predetermined OCP. Ex-vivo experiments were performed on a fresh pig bladder with 4 cm cuff placed around the urethra. Leak point pressure with different predetermined OCP values was successively measured during cystometry via a catheter at the bladder dome.Results: Our in-vitro and ex-vivo experiments demonstrated that these three novel AUSs provided stable and predetermined OCP — within the physiological range — and completely deflated the cuff, when required, in a limited time compatible with physiological voiding cycles.Conclusions: Our three novel, remotely controlled AUSs showed promising results that should be confirmed by in-vivo experiments focusing on efficacy and safety.