Open AccessAcute urinary retention secondary to urethral involvement of granulomatosis with polyangiitis
Author(s) -
Patrick T. Anderson,
Stephanie Gottheil,
Manal Gabril,
Lillian Barra,
Nicholas Power
Publication year - 2017
Publication title -
canadian urological association journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.477
H-Index - 38
eISSN - 1920-1214
pISSN - 1911-6470
DOI - 10.5489/cuaj.3555
Subject(s) - medicine , granulomatosis with polyangiitis , cyclophosphamide , malignancy , genitourinary system , systemic vasculitis , urinary system , etiology , vasculitis , necrotizing vasculitis , urinary retention , dermatology , pathology , urology , chemotherapy , disease
Granulomatosis with polyangiitis (GPA, formerly Wegener’s granulomatosis) is a systemic necrotizing vasculitis of small- and medium- sized blood vessels, primarily affecting the upper and lower respiratory tracts, as well as the kidneys. Urogenital manifestations of GPA are exceedingly rare and usually respond well to systemic immunosuppressive therapy. Here, we present a case of a 36-yearold female presenting with acute urinary obstruction secondary to urethral GPA involvement in the immediate postpartum period. Special consideration should be given to ruling out malignancy in all patients with a history of GPA and urethral lesions, especially when there is a history of cyclophosphamide treatment.