3D Lipidic Matrix for Incorporation and Stabilization of Biologically Active Molecules | Zendy

Martina Zatloukalová | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

3D Lipidic Matrix for Incorporation and Stabilization of Biologically Active Molecules

Author(s) -

Martina Zatloukalová

Publication year - 2022

Publication title -

chemické listy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.137

H-Index - 28

eISSN - 1213-7103

pISSN - 0009-2770

DOI - 10.54779/chl20220172

Subject(s) - lyotropic , bioavailability , amphiphile , lyotropic liquid crystal , aqueous solution , biological activity , molecule , biomolecule , solubility , hexagonal phase , chemistry , hexagonal crystal system , amphiphilic molecule , organic chemistry , phase (matter) , matrix (chemical analysis) , chemical engineering , materials science , nanotechnology , combinatorial chemistry , liquid crystalline , chromatography , crystallography , biochemistry , polymer , in vitro , copolymer , bioinformatics , engineering , biology

In aqueous media, biologically active substances are usually unstable, poorly soluble compounds with low bioavailability. Incorporation of these compounds into the structure of lipid-based lyotropic liquid crystalline phase or nanoparticles can increase their solubility and subsequent bioavailability. The aim of this review is to clarify the principle of self-assembly of lipidic amphiphilic molecules in the aqueous environment, to present lipid bicontinuous cubic and hexagonal phases and their current biological application.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research