Open AccessAntidiabetic, Thrombolytic, Antimicrobial, Antioxidant and Cytotoxicity Studies of Brinjal (Solanum Melongena) Leaves Extracts
Author(s) -
Muhammad Sohail Riaz,
Rabia Saqlain,
Shabbir Hussain,
Muhammad Afzal,
Rehman Qadir
Publication year - 2021
Publication title -
lgu journal of life sciences
Language(s) - English
Resource type - Journals
eISSN - 2521-0130
pISSN - 2519-9404
DOI - 10.54692/lgujls.2021.0502150
Subject(s) - dpph , solanum , solanum nigrum , chemistry , phytochemical , flavonoid , ethyl acetate , food science , antimicrobial , antioxidant , melongena , traditional medicine , botany , biology , chromatography , biochemistry , organic chemistry , medicine
Phytochemical, antioxidant, cytotoxicity, antimicrobial, and antidiabetic of brinjal (Solanum melongena) leave extracts in the present study. The selected plant material was dipped in different polarity-based solvents for one weak such as chloroform, n-hexane, methanol, ethyl acetate, and n-butanol. By using spectroscopic techniques total phenolic contents (TPC) and total flavonoid contents (TFC) were analyzed. The range of total phenolic contents was 159.48 ± 1.49 to 23.19 ± 0.40 GAE mg/100 g. The range of total flavonoid contents was 4.87± 0.28 to 29.6 ± 0.24 CE mg/100 g. Extracts had an antioxidant activity which was evaluated by using free radical scavenging DPPH assay. Total phenolic contents and the ratio inhibition in linoleic acid oxidation were also calculated. The present study result revealed that the leaves of the Solanum melongena plant may be the main source of natural antioxidants and it is also used as an antidiabetic activity. In the present study, the potential of extracts against the selected bacterias (Bacillus subtilis and Escherichia coli) and fungi (Fusarium solani and Aspergillus nigar) was evaluated. The plant extracts were examined against human red blood cells (RBCs) and the percentage lysis was also found in this research work. Statistical data analysis was done by Analysis of variance (ANOVA) using SPSS version 21.0.