Open AccessEffects of timolol maleate eye drops on experimentally dilated cardiomyopathy and healthy rabbits
Author(s) -
Mitsuhiro Isaka,
Reimi Hayashida,
Yuumi Tamashima,
Ryuji Araki
Publication year - 2021
Publication title -
open veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.39
H-Index - 10
eISSN - 2226-4485
pISSN - 2218-6050
DOI - 10.5455/ovj.2021.v11.i3.9
Subject(s) - timolol , dilated cardiomyopathy , medicine , heart rate , ejection fraction , circulatory system , anesthesia , cardiomyopathy , intraocular pressure , blood pressure , cardiology , heart failure , ophthalmology
Dilated cardiomyopathy (DCM) is the most frequently diagnosed cardiomyopathy in rabbits. Timolol maleate (nonselective beta-blockers), which reduces the heart rate (HR) and blood pressure, has been used for glaucoma. However, this effect has not been assessed in a rabbit DCM model.