Open AccessTotal Serum Immunoglobulin E Levels in Patients with Psoriasis
Author(s) -
Emina Kasumagić-Halilović
Publication year - 2020
Publication title -
materia socio-medica/materia socio medica
Language(s) - English
Resource type - Journals
eISSN - 1986-597X
pISSN - 1512-7680
DOI - 10.5455/msm.2020.32.105-107
Subject(s) - psoriasis , immunoglobulin e , medicine , pathogenesis , immunology , antibody , inflammation , allergy , disease , family history
Psoriasis is a common chronic skin disorder characterized by inflammation and abnormal epidermal proliferation. Its severity ranges from a chronic plaque psoriasis (CPP) to generalized psoriatic erythroderma (PE). The cause of psoriasis is unknown although most evidence supports the hypothesis that psoriasis is an immunologically mediated disease. The T-helper (Th) 1 and Th17 cells are responsible for the inflammation of psoriasis. Immunoglobulin E (IgE) is a class of immunoglobulin essential for the allergic response. There is some evidence that IgE may take a part in the pathogenesis of psoriasis.