Open AccessIdiopathic Membranous Nephropathy and Treatment Related Complications
Author(s) -
Snežana Unčanin,
Jasminka Džemidžić,
Nafija Serdarević,
Alma Muslimović,
Denis Hasković
Publication year - 2020
Publication title -
medicinski arhiv
Language(s) - English
Resource type - Journals
eISSN - 1986-5961
pISSN - 0350-199X
DOI - 10.5455/medarh.2020.74.228-232
Subject(s) - medicine , membranous nephropathy , proteinuria , nephrotic syndrome , nephritic syndrome , renal function , minimal change disease , glomerulonephritis , disease , gastroenterology , kidney , surgery , focal segmental glomerulosclerosis
Idiopathic Idiopathic membranous nephropathy (iMN) is an immune-complex mediated renal disease which is usually associated with the nephrotic syndrome (NS). The course of the disease is variable. Some patients maintain normal kidney function with or without a spontaneous remission of proteinuria, while others progress to end-stage renal failure or die from complications related to the nephrotic syndrome. Whether or not to treat a patient with idiopathic membranous nephropathy is still controversial. The controversy is mainly related to the toxicity of the therapy and the variable natural course of the disease-spontaneous remission occurs in 40-50% of patients.