Open Accessand #945;-Glucosidase and and #945; -amylase inhibitory activities of Mukia maderaspatana (L) Roem
Author(s) -
Vadivelan Ramachandran
Publication year - 2012
Publication title -
journal of intercultural ethnopharmacology
Language(s) - English
Resource type - Journals
ISSN - 2146-8397
DOI - 10.5455/jice.20120616023239
Subject(s) - amylase , inhibitory postsynaptic potential , chemistry , botany , biology , enzyme , biochemistry , neuroscience
Aim:The present study is to evaluate the invitro antidiabetic activity of Mukia maderaspatana ethanolic extract and fractions by and #945;-glucosidase and and #945; -amylase inhibitory activity.Methods:Inorder to evaluate if the extraction procedure could influence the activity, we decided to extract with ethanol and fractions with chloroform and n-butanol of Mukia maderaspatana and test each of them with enzyme and #945;-glucosidase and and #945; -amylase inhibitory activity .Results:Mukia maderaspatana ethanolic extract and fractions showed dose dependent inhibition of and #945;-glucosidase and and #945; -amylase enzyme and exhibited lower inhibitory activity than acarbose.Conclusion:The study revealed the antidiabetic potential and could be helpful to develop medicinal preparations and nutraceuticals and function foods for diabetes. [J Intercult Ethnopharmacol 2012; 1(2.000): 97-100