Open AccessWhite matter abnormalities and Virchow Robin spaces in patients with psychotic disorders
Author(s) -
Osman Özdemir,
Pınar Güzel Özdemir,
Vedat Çilingir,
Mehmet Bulut,
Damla Timucin
Publication year - 2014
Publication title -
disease and molecular medicine
Language(s) - English
Resource type - Journals
ISSN - 2147-6748
DOI - 10.5455/dmm.20140510085049
Subject(s) - medicine , white (mutation) , white matter , pediatrics , radiology , magnetic resonance imaging , biochemistry , chemistry , gene
In this study, we aimed to present white matter abnormalities and Virchow Robin spaces in patients with psychotic disorders and to discuss possible underlying mechanisms. The patient sample comprised 24 patients with psychotic disorders who had white matter abnormalities on MRI. Magnetic resonance imaging (MRI) appeared periventricular white matter changes in twelve patients (%50,0), frontal lesions in six patients (%25,0), parietal lesions in six patients (%25,0), temporal lesions in one patients (%4,2), infratentorial lesions in two patients (%8,3), and Virchow Robin spaces in eight patients (%33,3) This study suggested that there is a relationship between white matter abnormalities and psychotic disorders. [Dis Mol Med 2014; 2(2.000): 21-27