Open AccessCerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review
Author(s) -
Náthalie Angélica Cardoso Marqui,
Marina Lucca de Campos Lima,
Rafaela de Fátima Ferreira Baptista,
Rawene Elza Veronesi Gonçalves Righetti,
Tauane Rene Martins,
Gabrielle Gomides Marconato,
Gabriella Cavalcante Leite,
Kamila Cristina Viana,
Beatriz Nomada Hauy,
Jaqueline Modaelli,
Airton José Mendes
Publication year - 2021
Publication title -
mednext journal of medical and health sciences
Language(s) - English
Resource type - Journals
ISSN - 2763-5678
DOI - 10.54448/mdnt2141
Subject(s) - medicine , antibiotics , abscess , mortality rate , brain abscess , antibiotic therapy , disease , surgery , broad spectrum , intensive care medicine , microbiology and biotechnology , biology , chemistry , combinatorial chemistry
Objective: To report a Central Nervous System infection evolving with brain abscess and to address aspects of the treatment of the disease. Results: even with advances in treatment and diagnosis, the pathology has a high mortality. However, the best prognosis is noticed when there is a suspicion through the clinic, neuroradiological images readily available, antimicrobial therapy against commonly encountered agents, and surgical drainage procedures. One study, which combined antibiotic therapy and surgery to drain the abscess, in most of the cases, studied, demonstrated a mortality rate of 12%, and another study, a 42% mortality rate when using antibiotic therapy alone. Another reference suggests the use of antibiotic therapy alone in less severe cases with less neurological impairment. Neurological clinical sequelae can be found in up to 30% of cases. The time of antibiotic therapy still needs to be debated, as well as the surgical indication for drainage. Final Considerations: Pediatric brain abscess is an uncommon disease, still with high morbidity and mortality. Surgical drainage or excision of pediatric abscesses remains the basis of treatment both to relieve the mass effect and to provide a microbiological diagnosis. The literature demonstrates that broad-spectrum antibiotics and access to CT and MRI images decrease the rates of morbidity and mortality. It is concluded that the therapeutic approach involves the administration of broad-spectrum intravenous antibiotics and surgical drainage in more complex cases.