Open AccessTherapeutic effect of garlic containing S-allyl cysteine and Diallyl-di-sulfide on improving blood lipid profile
Author(s) -
Ayesha Siddiqa,
Shahnai Basharat,
Fizza Mubarik,
Fatima Farooq,
Muhammad Ali
Publication year - 2022
Publication title -
pakistan biomedical journal
Language(s) - English
Resource type - Journals
eISSN - 2709-2798
pISSN - 2709-278X
DOI - 10.54393/pbmj.v5i1.110
Subject(s) - allicin , hyperlipidemia , alliin , diallyl disulfide , lipid profile , chemistry , traditional medicine , medicine , food science , cholesterol , pharmacology , biochemistry , endocrinology , diabetes mellitus , apoptosis
Cardiovascular-related diseases are considered as the major risk for health and may lead to many illnesses. Hyperlipidemia is the highest common cause of diseases related to heart known as CHD. Since ancient times, innumerable herbs and organic foods are used to treat diseases among which garlic has been shown beneficial for treating hyperlipidemia and normalizing lipid profile levels. Garlic may be used in different forms like powder, tablets, extracts or after ageing. Its sulfur containing compounds like allicin, S-allylcysteine, alliin, ajoene, diallyl disulfide are proven to have the pharmacological benefits. The main aim of the current review is to analyze and evaluate the studies regarding anti-hyperlipidemic effects of garlic and its supplements on normalizing lipid profile among hyperlipidemicsubjects.After analyzing different studies being carried out earlier, it is concluded that garlic is effective in managing lipid profile including total cholesterol, triglycerides, LDL, HDL levels among people with hyperlipidemia ranging from mild to moderate intensity.