Open AccessPemphigus foliaceus in a sheep
Author(s) -
Evani Souza de Oliveira Strada,
Robério Rodrigues Silva,
Gleidson Giordano Pinto de Carvalho,
Larissa Pires Barbosa,
Ivanor Nunes do Prado,
Fabiana Lana de Araújo,
Luis Henrique de Almeida Matos,
Olga Teresa Barreto Cruz,
Dorgival Morais de Lima Júnior
Publication year - 2019
Publication title -
semina. ciências agrárias
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 25
eISSN - 1679-0359
pISSN - 1676-546X
DOI - 10.5433/1679-0359.2019v40n2p993
Subject(s) - pemphigus foliaceus , dermatology , medicine , acanthosis , pemphigus , pathology , hyperkeratosis , erythroderma , abdomen , anatomy , immunology , autoantibody , antibody
Pemphigus foliaceus (PF) is an autoimmune disease of the skin and is the most common form of pemphigus in domestic animals. This work reports a case of pemphigus foliaceus in a Santa Inês hair sheep. The ewe presented with multifocal bilateral crusted alopecic dermatitis affecting the chest, abdomen, and pelvic and thoracic limbs. Parakeratotic hyperkeratosis and acanthosis, in addition to subcorneal pustules, were observed histologically, and acantholytic cells and neutrophils were observed within the pustules. In the superficial and deep dermal tissues, there was intense eosinophilic infiltration and the presence of rare macrophages. These microscopic findings were characteristic of PF, and treatment with dexamethasone was ineffective. This disease is rare in sheep, and this is the first case report to be published in Brazil.