Open AccessImaging pattern and histological features of Gorham-Stout Disease of the radius
Author(s) -
Clemence Bruyere,
Valentina Garibotto,
AnneLaure Rougemont,
Sana Boudabbous
Publication year - 2018
Publication title -
journal of solid tumors
Language(s) - English
Resource type - Journals
eISSN - 1925-4075
pISSN - 1925-4067
DOI - 10.5430/jst.v8n2p20
Subject(s) - medicine , magnetic resonance imaging , osteolysis , radiology , positron emission tomography , ossification , radiography , hyperintensity , differential diagnosis , etiology , soft tissue , lesion , nuclear medicine , pathology , anatomy
Gorham-Stout Disease (GD) is a very rare disease of unknown etiology characterized by progressive osteolysis and soft tissue involvement. Imaging is non-specific, and diagnosis may be delayed. The evolution of the disease is unpredictable, with progression of the osteolysis, spontaneous regression, or in a few cases re-ossification. We report a case of a 54-year-old woman with GD of the radius. In this rare location, only few cases have been reported with all imaging modalities: conventional radiography, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET-CT). We describe the characteristics of GD in different imaging modalities, as well as the histological features. To the best of our knowledge, we report the first metabolically active lesion in GD, with relevant implications for the differential diagnosis.