Open AccessAssociation between 18F-FDG PET/CT and MRI appearance of spinal leptomeningeal disease before and after treatment at a tertiary referral center
Author(s) -
Harry Papasozomenos,
Nandita Guha-Thakurta,
Rory R. Mayer,
Jeffrey S. Weinberg,
Morris D. Groves,
J. Matthew Debnam
Publication year - 2015
Publication title -
journal of solid tumors
Language(s) - English
Resource type - Journals
eISSN - 1925-4075
pISSN - 1925-4067
DOI - 10.5430/jst.v6n1p1
Subject(s) - medicine , radiology , cerebrospinal fluid , cytology , spinal canal , magnetic resonance imaging , nuclear medicine , pathology , spinal cord , psychiatry
Leptomeningeal disease (LMD), the presence of metastasis in the subarachnoid space, has devastating implications if left untreated. The gold standard for LMD diagnosis is cytologic analysis of cerebrospinal fluid (CSF); MRI is also used to evaluate suspected LMD. The purpose of this study was to compare the appearance of LMD in the spinal canal on 18 F-FDG PET/CT imaging with the appearance of LMD on MRI and with CSF cytology.