Open AccessEmbryo coculture: A review
Author(s) -
A.P. Melnick,
Steven D. Spandorfer
Publication year - 2015
Publication title -
journal of epidemiological research
Language(s) - English
Resource type - Journals
eISSN - 2377-9330
pISSN - 2377-9306
DOI - 10.5430/jer.v2n1p15
Subject(s) - embryo , in vitro fertilisation , in vitro , microbiology and biotechnology , somatic cell , biology , embryo culture , andrology , embryogenesis , medicine , genetics , gene
Since the inception of in-vitro fertilization, various attempts have been made to improve in-vitro embryo development, therebyenhancing implantation and in turn, pregnancy rates. Coculture, the simultaneous culture of somatic cells together with theembryo, is one strategy that has been used to achieve this goal. We review the rationale behind the technique of coculture, currentmethods utilized, and the evidence supporting its use.