Open AccessFunctional MRI demonstrates pain perception in hand osteoarthritis has features of central pain processing
Author(s) -
Nidhi Sofat,
Monika Hermansson,
Matthew A. Howard,
Emma H. Baker,
Franklyn A. Howe,
Thomas R. Barrick
Publication year - 2013
Publication title -
journal of biomedical graphics and computing
Language(s) - English
Resource type - Journals
eISSN - 1925-4016
pISSN - 1925-4008
DOI - 10.5430/jbgc.v3n4p20
Subject(s) - osteoarthritis , medicine , somatosensory system , cingulate cortex , visual analogue scale , chronic pain , analgesic , physical medicine and rehabilitation , physical therapy , anesthesia , central nervous system , pathology , psychiatry , alternative medicine
Hand osteoarthritis (HOA) is typified by pain and reduced function. We hypothesised that people with HOA have enhanced sensitivity and activation of peripheral nociceptors in the hand, thereby potentiating chronic pain. In our study we aimed to assess if central sensitisation mediates pain perception in osteoarthritis of the hand.