Functional MRI demonstrates pain perception in hand osteoarthritis has features of central pain processing | Zendy

Nidhi Sofat | Zendy; Monika Hermansson | Zendy; Matthew Howard | Zendy; Emma H. Baker | Zendy; Franklyn A. Howe | Zendy; Thomas R. Barrick | Zendy

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Functional MRI demonstrates pain perception in hand osteoarthritis has features of central pain processing

Author(s) -

Nidhi Sofat,

Monika Hermansson,

Matthew Howard,

Emma H. Baker,

Franklyn A. Howe,

Thomas R. Barrick

Publication year - 2013

Publication title -

journal of biomedical graphics and computing

Language(s) - English

Resource type - Journals

eISSN - 1925-4016

pISSN - 1925-4008

DOI - 10.5430/jbgc.v3n4p20

Subject(s) - osteoarthritis , medicine , somatosensory system , cingulate cortex , visual analogue scale , chronic pain , analgesic , physical medicine and rehabilitation , physical therapy , anesthesia , central nervous system , pathology , psychiatry , alternative medicine

Hand osteoarthritis (HOA) is typified by pain and reduced function. We hypothesised that people with HOA have enhanced sensitivity and activation of peripheral nociceptors in the hand, thereby potentiating chronic pain. In our study we aimed to assess if central sensitisation mediates pain perception in osteoarthritis of the hand.

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