Open AccessLymphangioleiomyomatosis: An unusual age of diagnosis with literature review
Author(s) -
Alaoui Lamrani Youssef,
Badr Alami,
F. Sahnoun,
Meriem Boubbou,
Imane Kamaoui,
Mustapha Maâroufi,
N. Sqalli Houssaini,
B. Amara,
S. Tizniti
Publication year - 2014
Publication title -
international journal of diagnostic imaging
Language(s) - English
Resource type - Journals
eISSN - 2331-5865
pISSN - 2331-5857
DOI - 10.5430/ijdi.v1n1p17
Subject(s) - lymphangioleiomyomatosis , medicine , differential diagnosis , rare disease , pathophysiology , lymphangiomatosis , menopause , pathology , disease , radiology , tuberous sclerosis , lymphatic system
Lymphangioleiomyomatosis (LAM) is a rare idiopathic disorder of unclear origin, which almost exclusively occurs to women before menopause. It is characterized by nonneoplastic diffuse proliferation of atypical immature smooth muscle cells around small airways and vessels. We report the case of a 64-year-old woman kept for chronic progressive dyspnea related to a diffuse LAM.The discussion includes a literature review that describes the physiopathology, clinical features, chest computed tomography aspects, and differential diagnosis regarding this rare disease.Through this case report, pulmonary LAM should be included in the list of differential diagnoses for cases of pulmonary cystic lesions, even in postmenopausal women.