Open AccessAtypical Sjögren presentation of pruriginous rash and mild eosinophilia with minor sicca symptoms: A case report
Author(s) -
Noemie Tremblay,
Alexandra E Bourque,
Jean-Pascal Costa
Publication year - 2018
Publication title -
case reports in internal medicine
Language(s) - English
Resource type - Journals
eISSN - 2332-7251
pISSN - 2332-7243
DOI - 10.5430/crim.v5n1p18
Subject(s) - medicine , dermatology , rash , eosinophilia , hydroxychloroquine , sicca syndrome , biopsy , population , pathology , disease , covid-19 , infectious disease (medical specialty) , environmental health
We report a case of an 82-year-old woman diagnosed with Sjögren syndrome on the basis of salivary gland biopsy and anti-Ro/SSA antibodies who presented to our institution with a pruriginous maculopapular pancorporeal rash with diffuse eosinophilic infiltrate and mild eosinophilia. Sicca symptoms were mild. Cutaneous and hematologic findings resolved spontaneously within 4 weeks, the rash did not respond to antihistamines but was mildly attenuated by topical corticosteroid. Both the rash and hypereosinophilia greatly improved while the patient received oral corticosteroids for a contrast medium allergy before a CT-scan. When the patient was diagnosed with SS, hydroxychloroquine treatment was introduced. This case report aims to raise awareness of the possibility of such a clinical presentation, considering the known increased risk of non-hodgkin lymphoma associated with Sjögren syndrome estimated to 5%-10% lifetime risk which is 5 to 44 times higher than that of the general population.