Open AccessRenal insufficiency as a primary manifestation of sarcoidosis in a 13-year-old boy
Author(s) -
Wael Nasser,
Safori Gassan,
Soboh Soboh,
Farid Nakhoul
Publication year - 2016
Publication title -
case reports in internal medicine
Language(s) - English
Resource type - Journals
eISSN - 2332-7251
pISSN - 2332-7243
DOI - 10.5430/crim.v4n1p17
Subject(s) - medicine , sarcoidosis , nephrocalcinosis , nephrology , etiology , renal biopsy , gastroenterology , biopsy , pathology , kidney
Background: Childhood sarcoidosis is a multisystem granulomatous disorder of unknown etiology. The disease affects childrenaged 13-15 years, especially the lungs.Objective: We describe a 13-year-old boy who presented to our pediatric nephrology division due to acute renal failure, cutaneousrash and anemia.Methods: Percutaneous kidney biopsy was performed showing non-caseating granulomas with mononuclear infiltrates.Results: Mantoux test and serology for Brucella were negative. Chest radiograph showed minimal, bilateral infiltrates. Renalultrasound showed nephrocalcinosis. Pulmonary functions study demonstrated mild restrictive disturbance. Plasma creatininewas 1.8 mg/dl and calcium 12.3 mg/dl.Conclusion: In the current patient, renal insufficiency was discovered while exploring constitutional symptoms in a 13-year-oldchild. Early diagnosis and adapted treatment allows preserving renal function.