Open AccessRecurrence of a de-differentiated liposarcoma of the colon
Author(s) -
Mairéad M. Hennessy,
J E A O'Connell,
David Kearney,
Emmet Andrews
Publication year - 2017
Publication title -
case reports in clinical pathology
Language(s) - English
Resource type - Journals
eISSN - 2331-2734
pISSN - 2331-2726
DOI - 10.5430/crcp.v4n2p24
Subject(s) - medicine , radiology , lesion , magnetic resonance imaging , laparotomy , biopsy , differential diagnosis , liposarcoma , iliac fossa , chemotherapy , surgery , sarcoma , pathology
We present the case of a 56-year-old gentleman who presented with non specific malaise, myalgia and anorexia. Clinical examination revealed a large circumscribed palpable mass in the left iliac fossa. He underwent an intraabdominal pelvic biopsy, computed tomography (CT), magnetic resonance imaging (MRI) of abdominal wall and Positron Emmission Tomography (PET). Differential diagnoses included Gastro Intestinal Stromal Tumour (GIST) and sarcoma. He underwent a laparotomy and excision of the lesion. Histological analysis of the lesion demonstrated a dedifferentiated liposarcoma involving the colon and adjacent pericolic fat. Margins were clear and there was no nodal involvement. He declined adjuvant chemotherapy. He subsequently developed a local recurrence, which was deemed unresectable. He commenced chemotherapy but continued to deteriorate. He received palliative treatment and died 6 months following his initial surgery.