Open AccessUltrasound guided fine needle aspiration cytology diagnosis of collision tumor in a lymph node: Lymphoma and metastatic adenocarcinoma
Author(s) -
Qian Wang,
Dhanalaksmi Balakrishnan,
Maoxin Wu
Publication year - 2017
Publication title -
case reports in clinical pathology
Language(s) - English
Resource type - Journals
eISSN - 2331-2734
pISSN - 2331-2726
DOI - 10.5430/crcp.v4n2p1
Subject(s) - medicine , fine needle aspiration , lymph node , adenocarcinoma , lymphoma , supraclavicular lymph nodes , biopsy , pathology , chronic lymphocytic leukemia , lymph node biopsy , lung cancer , radiology , lung , cancer , metastasis , leukemia
Diagnosis of two distinct malignancies in a single sample is rare. Here we report a case of lung adenocarcinoma metastasized to a supraclavicular lymph node which was concomitantly diagnosed with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) using ultrasound-guided fine needle aspiration biopsy (US-FNA) sample.A 62-year-old Caucasian male presented with cough and bloody sputum. US-FNA of a supraclavicular lymph node showed two distinct cell populations and, based on morphological examination and immunohistochemical staining of the FNA cell block slides, diagnosed with CLL/SLL and metastatic lung adenocarcinoma. Flow cytometric analysis of peripheral blood supported the diagnosis of CLL/SLL. To our knowledge, this is a rarely reported cytology case in which metastatic lung adenocarcinoma is concurrently diagnosed with CLL/SLL in a single lymph node and can be diagnosed based an FNA sample.