Open AccessFirst pre-filled pen device with highly purified human menopausal gonadotropin (HP-hMG, Menopur) in liquid is shown to be bioequivalent to powder for reconstitution
Author(s) -
Daniël M. Jonker,
Manuela C. Koch,
Petter Larsson,
Arjun Ravi,
Birgitte Buur Rasmussen,
Runa Speer,
Bernadette Mannaerts
Publication year - 2021
Publication title -
international journal of clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.363
H-Index - 67
ISSN - 0946-1965
DOI - 10.5414/cp204040
Subject(s) - bioequivalence , cmax , crossover study , pharmacokinetics , menotropins , geometric mean , follicle stimulating hormone , gonadotropin , confidence interval , pharmacology , medicine , endocrinology , adverse effect , ovulation , hormone , luteinizing hormone , ovulation induction , mathematics , statistics , alternative medicine , pathology , placebo
To determine whether serum human follicle-stimulating hormone (FSH) levels after single subcutaneous dosing of highly purified human menopausal gonadotropins (HP-hMG) in a liquid formulation and a powder formulation are bioequivalent.