Open AccessAnaphylaxis in middle-aged patients
Author(s) -
Wojciech Francuzik,
Magdalena Kraft,
Kathrin Scherer,
Franziska Ruëff,
Claudia Pföhler,
Regina Treudler,
Roland Lang,
Thomas Hawranek,
Nicola Wagner,
Margitta Worm
Publication year - 2021
Publication title -
allergologie select
Language(s) - English
Resource type - Journals
ISSN - 2512-8957
DOI - 10.5414/alx02216e
Subject(s) - anaphylaxis , medicine , allergy , immunology
Age is one of the most important factors influencing the course of anaphylaxis: moreover, the frequency of elicitors of anaphylaxis is age-associated. We analyzed 8,465 anaphylactic episodes in adult patients in three age groups with a focus on patients in the middle-age group (35 - 65 years old). Insect venom was the most frequent trigger in this age group (51.2%) followed by drugs (22.8%) and food (17.3%). Severe reactions were observed in 40.1% of middle-aged patients and occurred more frequently in this age group than in patients below 35 years (27.6%) and less frequently than in patients over 65 years (55.6%). The symptoms and comorbidity profile also changed with age, most significantly regarding the increase in rates of concomitant cardiologic diseases and (severe) cardiovascular symptoms.