Open AccessA simple scoring system in COVID-19 patients with neurological manifestations
Author(s) -
Hatice Yüksel,
Ebru Bilge Dirik,
Görkem Tutal Gürsoy,
Özlem Öztürk Tan,
Hesna Bektaş,
Levent Yamanel,
Rahmet Güner
Publication year - 2021
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.138
H-Index - 16
ISSN - 1823-6138
DOI - 10.54029/2021rrf
Subject(s) - procalcitonin , medicine , gastroenterology , mean platelet volume , d dimer , covid-19 , neutrophil to lymphocyte ratio , lymphocyte , disease , platelet , sepsis , infectious disease (medical specialty)
Background: Coronavirus disease 2019 (COVID-19) has affected a rapidly growing patient population worldwide. To effectively manage the disease, physicians need tests or methods that classify patients according to their risks. Our aim is to determine the importance of mean platelet volume (MPV), neutrophil-lymphocyte ratio (NLR), MPVNLR score (MPV×Neutrophil/lymphocyte) in predicting the clinical course and mortality in hospitalized COVID-19 patients with neurological manifestations.Methods: A total of 300 patients were enrolled in the study. MPV, NLR, MPVNLR score, CRP, D-dimer, IL-6, and procalcitonin tests were obtained for each patient.Results: MPV, NLR, MPVNLR score, IL-6, D-dimer, procalcitonin, and CRP in the non-survivor group were higher than the survivor group (p=0.001, p:0.001, p=0.001, p=0.001, p=0.001, p=0.027, and p=0.001, respectively). MPV, NLR, MPVNLR score, IL-6, D-dimer, procalcitonin and CRP were higher in patients with altered mental status (p=0.001, p=0.001, p=0.001, p=0.014, p=0.002, p=0.026, and p=0.001, respectively).Conclusion: High MPV, NLR, and MPVNLR scores may be simple markers to predict mortality and mental deterioration in COVID-19.